D-Histidine CAS:351-50-8 98.5%~101.0%
Solubility in water |
Colorless & clear (c=3) |
Specific rotation [α]D20 |
-11.8°~-12.8°(c= 11, 6M-HCl) |
Loss on drying |
Not more than 0.3% |
Residue on ignition (as sulfate) |
Not more than 0.1% |
Chloride (Cl) |
Not more than 0.02% |
Sulfate (SO4) |
Not more than 0.03% |
Heavy metals (as Pb) |
Not more than 10ppm |
Iron (Fe) |
Not more than 10ppm |
Ammonium (NH4) |
Not more than 0.02% |
Arsenic (As2O3) |
Not more than 1ppm |
Other amino acids |
Not detected by T.L.C.(The spotted amount, 20μg) |
Assay |
98.5%~101.0% |
L-Isomer |
Not more than 0.5% |
D-Histidine may be used in the design of peptide drugs, cationic peptides, such as analogues of carnosine. D-Histidine may also be used as a heavy metal sequestration agent.
D-histidine is an optically active form of histidine having D-configuration. It has a role as a Saccharomyces cerevisiae metabolite. It is a D-alpha-amino acid and a histidine. It is a conjugate base of a D-histidinium(1+). It is a conjugate acid of a D-histidinate(1-). It is an enantiomer of a L-histidine. It is a tautomer of a D-histidine zwitterion.
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