N-Acetyl-L-Phenylalanine CAS:2018-61-3 98.5%～101.0%
|
Solubility in methanol |
Colorless & almost clear (c=5) |
|
Specific rotation [α]D25 |
+38.0°～+41.0°(c= 5, methanol) |
|
Loss on drying |
Not more than 0.5% |
|
Residue on ignition (as sulfate) |
Not more than 0.2% |
|
Chloride (Cl) |
Not more than 0.05% |
|
Sulfate (SO4) |
Not more than 0.02% |
|
Heavy metals (as Pb) |
Not more than 15ppm |
|
Arsenic (As2O3) |
Not more than 1ppm |
|
Assay |
Not less than 98.5% |
N-acetyl-L-phenylalanine is the N-acetyl derivative of L-phenylalanine. It has a role as a metabolite. It is a N-acyl-L-phenylalanine, a N-acetyl-L-amino acid and a N-acetylphenylalanine. It is a conjugate acid of a N-acetyl-L-phenylalaninate. It is an enantiomer of a N-acetyl-D-phenylalanine.
Acetylphenylalanine is a hazardous amphipathic metabolite of phenylalanine. It appears in large amount in urine of patients with phenylketonuria which is a human genetic disorder due to the lack of phenylalanine hydroxylase, the enzyme necessary to metabolize phenylalanine to tyrosine. Acetylphenylalanine is a product of enzyme phenylalanine N-acetyltransferase [EC 2. 3. 1. 53] in the pathway phenylalanine metabolism. (KEGG; Wikipedia).
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